Journal of Stroke & Cerebrovascular Diseases
Volume 17, Issue 3 , Pages 121-128 , May 2008

Comparison of Combined Venous and Arterial Thrombolysis with Primary Arterial Therapy Using Recombinant Tissue Plasminogen Activator in Acute Ischemic Stroke

  • Thomas Wolfe, MD

      Affiliations

    • Department of Neurology, Medical College of Wisconsin/Froedtert Hospital, Milwaukee, Wisconsin
    • ,
  • Jose I. Suarez, MD

      Affiliations

    • Department of Neurology, Case Medical Center/Case Western Medical School, Cleveland, Ohio
    • ,
  • Robert W. Tarr, MD

      Affiliations

    • Department of Neuroradiology, Case Medical Center/Case Western Medical School, Cleveland, Ohio
    • ,
  • Elisabeth Welter, MS

      Affiliations

    • Department of Neurology, Case Medical Center/Case Western Medical School, Cleveland, Ohio
    • ,
  • Dennis Landis, MD

      Affiliations

    • Department of Neurology, Case Medical Center/Case Western Medical School, Cleveland, Ohio
    • ,
  • Jeffrey L. Sunshine, MD, PhD

      Affiliations

    • Department of Neuroradiology, Case Medical Center/Case Western Medical School, Cleveland, Ohio
    • ,
  • Osama O. Zaidat, MD, MS

      Affiliations

    • Department of Neurology, Medical College of Wisconsin/Froedtert Hospital, Milwaukee, Wisconsin
    • Department of Neurological Surgery, Medical College of Wisconsin/Froedtert Hospital, Milwaukee, Wisconsin
    • Corresponding Author InformationAddress correspondence to Osama O. Zaidat, MD, MS, Neurology and Neurosurgery, Medical College of Wisconsin/Froedtert Hospital, 9200 W Wisconsin Ave, Milwaukee, WI 53226.

Received 4 September 2007 ,Revised 28 November 2007 ,Accepted 7 December 2007.

References 

  1. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. Tissue plasminogen activator for acute ischemic stroke. N Engl J Med. 1995;333:1581–1587
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  3. del Zoppo GJ, Higashida RT, Furlan AJ, et al. PROACT: A phase II randomized trial of recombinant pro-urokinase by direct arterial delivery in acute middle cerebral artery stroke; PROACT investigators, prolyse in acute cerebral thromboembolism. Stroke. 1998;29:4–11
  4. Suarez JI, Sunshine JL, Tarr R, et al. Predictors of clinical improvement, angiographic recanalization, and intracranial hemorrhage after intra-arterial thrombolysis for acute ischemic stroke. Stroke. 1999;30:2094–2100
  5. The IMS Study Investigators. Combined intravenous and intra-arterial recanalization for acute ischemic stroke: The interventional management of stroke study. Stroke. 2004;35:904–912
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  15. NINDS t-PA Stroke Study Group. Intracerebral hemorrhage after intravenous t-PA therapy for ischemic stroke. Stroke. 1997;28:2109–2118
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  22. Wolpert S, Bruckman H, Greenlee R, et al. rt-PA Acute Stroke Study Group Neuroradiologic evaluation of patients with acute stroke treated with recombinant tissue plasminogen activator: The rt-PA acute stroke study group. AJNR Am J Neuroradiol. 1993;14:3–13
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PII: S1052-3057(07)00204-2

doi: 10.1016/j.jstrokecerebrovasdis.2007.12.004

Journal of Stroke & Cerebrovascular Diseases
Volume 17, Issue 3 , Pages 121-128 , May 2008

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