Magnetic Resonance Angiography Findings in Patients with Ischemic Stroke from North India

Kumar, Gyanendra; Kalita, Jayantee; Kumar, Bishwanath; Bansal, Vikas; Jain, Sunil K.; Misra, UshaKant

doi:10.1016/j.jstrokecerebrovasdis.2009.03.012

« Previous Next »Journal of Stroke & Cerebrovascular Diseases
Volume 19, Issue 2 , Pages 146-152, March 2010

Magnetic Resonance Angiography Findings in Patients with Ischemic Stroke from North India

Gyanendra Kumar, MD
- Department of Neurology, University of Missouri-Health Care Columbia, Columbia, MO
Jayantee Kalita, MD, DM
- Department of Neurology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India
Bishwanath Kumar, MD
- Department of Neurology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India
Vikas Bansal, MD, DM
- Department of Neurology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India
Sunil K. Jain, MD
- Department of Radiology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India
UshaKant Misra, MD, DM
- Department of Neurology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India
- Address correspondence to UshaKant Misra, MD, DM, Department of Neurology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Raebareily Road, Lucknow, India.

Received 10 February 2009; received in revised form 13 March 2009; accepted 17 March 2009.

Background

We sought to evaluate the magnetic resonance (MR) angiography (MRA) findings in patients with ischemic stroke (IS) from North India and correlate the changes with various conventional and nonconventional risk factors.

Methods

The study took place at a tertiary care teaching hospital. The patients with IS were clinically evaluated including body mass index, dietary habits, and family history of stroke. MR imaging, MRA, and testing for blood sugar, lipid profile, B12, folic acid, and homocysteine were carried out. The MRA abnormalities were considered significant if stenosis was 50% or greater and these were categorized into extracranial (EC), intracranial (IC), or combined lesions. The location of infarct on MR imaging was also noted.

Results

There were 151 patients whose median age was 60 (22-85) years. The EC MRA was abnormal in 56.3% and the IC MRA in 63.3% of patients, the internal carotid artery being the most common site. Corresponding infarct was present in 64.7% and noncorresponding in 45.3% of patients. The MRA abnormality positively correlated with hypertension and diabetes, and negatively with alcohol consumption. The EC MRA abnormality was more common in upper caste Hindus and Muslims and in the city dwellers.