Case Reports| Volume 12, ISSUE 1, P47-48, January 2003

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A stroke-like presentation of glioblastoma multiforme

      A 69-year-old man presented to our hospital with an acute aphaisa. The patient had experienced headaches 27 months before this presentation and a magnetic resonance image (MRI) had been normal at that time. After a normal unenhanced head computed tomography (CT) scan was obtained, he received intravenous tissue plasminogen activator (t-PA) within 2 hours of the onset of his symptoms. The patient gradually improved, but on day 13, post t-PA–increased somnolence was noted. A repeat head CT scan showed acute hydrocephalus and a mass. The tumor did not respond to radiation treatment and the patient died 39 days after the initial presentation.
      Figure thumbnail gr1
      Fig. 1Unenhanced CT scans at days 0, 1, 9, and 13 after t-PA administration, and a normal MRI scan performed in 1996 (27 months before presentation). This pathological specimen shows the glioblastoma multiforme in the left hemisphere.
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