We hypothesized that left cerebral hemisphere infarction is more frequent than right
hemisphere infarction among young adults. Furthermore, we aimed to evaluate possible
causes for this asymmetry. Cases were found by computer search from hospital registries
at each of the 5 acute-care hospitals in a well-defined population in Hordaland County,
western Norway. Important parameters used in the analysis were derived from the patient
records. A total of 98 patients had left hemisphere infarctions, and 70 patients had
right hemisphere infarctions (P = .037). This difference was due mostly to the higher incidence of infarction in
the left middle cerebral artery (MCA) territory compared with the right MCA territory
among the male subjects (P = .016). Lacunar infarction was equally distributed, whereas nonlacunar infarction
was more frequent in the left MCA territory among the men (P = .016). A high frequency of left MCA infarctions may be associated with more frequent
atherosclerosis in the left carotid artery, lateralization of cortical functions,
or both in young adults.
Key Words
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References
- Ischemic stroke in adults younger than 30 years of age: cause and prognosis.Arch Neurol. 1987; 44: 479-482
- Large infarcts in the middle cerebral artery territory: etiology and outcome patterns.Neurology. 1998; 50: 341-350
- Functional recovery and social outcome after cerebral infarction in young adults.Cerebrovasc Dis. 1998; 8: 296-302
- The prognosis of ischemic stroke in young adults.Acta Neurol Scand. 1977; 55: 123-130
- Lateralization as a factor in the prognosis of middle cerebral artery territorial infarct.Eur Neurol. 2002; 48: 141-145
- Left hemispheric strokes in coronary surgery: implications for end-hole aortic cannulas.Ann Thorac Surg. 2001; 71: 128-132
- Difference in recognition of right and left hemispheric stroke.Lancet. 2005; 366: 392-393
- Stroke: the catch-up of underinvestigated topics.Lancet Neurol. 2006; 5: 10-11
- Interrater reliability of an etiologic classification of ischemic stroke.Stroke. 1995; 26: 46-51
- Classification of subtype of acute ischemic stroke: definitions for use in a multicenter clinical trial.Stroke. 1993; 24: 35-41
- Emotional behavior and hemispheric side of the lesion.Cortex. 1972; 8: 41-55
- Side asymmetries in hemispheric stroke [abstract].Cerebrovasc Dis. 1992; 2: 224
- Is there a side predilection for cerebrovascular disease?.Hypertension. 2003; 42: 56-60
- Baseline silent cerebral infarction in the Asymptomatic Carotid Atherosclerosis study.Stroke. 1994; 25: 1122-1129
- Silent cerebral infarction in patients enrolled in the TOAST study.Neurology. 1996; 46: 942-948
- Sex differences in lateralization revealed in the posterior language areas.Cereb Cortex. 2000; 10: 866-872
- Etiology of and risk factors for cerebral infarction in young adults in western Norway: a population-based case-control study.Eur J Neurol. 2004; 11: 25-30
- Bilateral symmetry of human carotid artery atherosclerosis.Stroke. 2002; 33: 2575-2580
- Protruding atheromas in the thoracic aorta and systemic embolization.Ann Intern Med. 1991; 115: 423-427
- Cerebrovascular disease: etiologic factors in cerebral infarction.Neurology. 1963; 13: 445-454
- Anatomy and functionality of leptomeningeal anastomoses: a review.Stroke. 2003; 34: 2750-2762
- Collateral circulation.Stroke. 2003; 24: 2279-2284
- Epidemiology of stroke in Innherred, Norway, 1994 to 1996: incidence and 30-day case-fatality rate.Stroke. 1997; 28: 2180-2184
- Transient ischemic attack: proposal for a new definition.N Engl J Med. 2002; 347: 1713-1716
Article info
Publication history
Accepted:
June 14,
2006
Received:
May 20,
2006
Identification
DOI: https://doi.org/10.1016/j.jstrokecerebrovasdis.2006.06.003
Copyright
© 2006 National Stroke Association. Published by Elsevier Inc. All rights reserved.