Background
We sought to evaluate the magnetic resonance (MR) angiography (MRA) findings in patients
with ischemic stroke (IS) from North India and correlate the changes with various
conventional and nonconventional risk factors.
Methods
The study took place at a tertiary care teaching hospital. The patients with IS were
clinically evaluated including body mass index, dietary habits, and family history
of stroke. MR imaging, MRA, and testing for blood sugar, lipid profile, B12, folic
acid, and homocysteine were carried out. The MRA abnormalities were considered significant
if stenosis was 50% or greater and these were categorized into extracranial (EC),
intracranial (IC), or combined lesions. The location of infarct on MR imaging was
also noted.
Results
There were 151 patients whose median age was 60 (22-85) years. The EC MRA was abnormal
in 56.3% and the IC MRA in 63.3% of patients, the internal carotid artery being the
most common site. Corresponding infarct was present in 64.7% and noncorresponding
in 45.3% of patients. The MRA abnormality positively correlated with hypertension
and diabetes, and negatively with alcohol consumption. The EC MRA abnormality was
more common in upper caste Hindus and Muslims and in the city dwellers.
Conclusion
In North Indian patients with IS, the frequency of EC and IC MRA abnormality lies
between Whites and the Orientals.
Key Words
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Article info
Publication history
Accepted:
March 17,
2009
Received in revised form:
March 13,
2009
Received:
February 10,
2009
Identification
DOI: https://doi.org/10.1016/j.jstrokecerebrovasdis.2009.03.012
Copyright
© 2010 National Stroke Association. Published by Elsevier Inc. All rights reserved.