Background
We estimated the stiffness parameter β (β value), which is useful in the assessment
of premature atherosclerosis, among patients with different subtypes of cerebral infarction
(CI; eg, small-vessel occlusion, large-artery atherosclerosis, cardioembolism, and
other determined and undetermined etiologies) to determine the clinical utility of
the β value in classification of stroke patients into CI subtypes.
Methods
Carotid ultrasonography (ALOKA ProSound SSD-alpha10) was performed in 31 CI patients
and 38 control subjects, and the β value of the bilateral common carotid artery at
2.0 cm proximal to the bifurcation was measured using the echo-tracking method. The
relationship between β value and age was examined, and the β value was compared among
the different CI subtypes.
Results
Positive β value correlated with age in control subjects (R = .69, P < .001) but not in CI patients (R = −.01, P = .996). There was no significant difference in the β value when comparing control
patients and patients with cardioembolic stroke (P = .106), but the β value were lower in patients with cardioembolic stroke than in
patients with noncardioembolic stroke (eg, small-vessel occlusion, large-artery atherosclerosis,
and others, P = .009).
Conclusions
The β value was lower in patients with cardioembolic stroke than in patients with
noncardioembolic stroke. The β value may be useful for estimating the risk of different
stroke subtypes.
Key Words
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Article info
Publication history
Published online: January 06, 2014
Accepted:
November 20,
2013
Received in revised form:
November 14,
2013
Received:
August 29,
2013
Footnotes
H.F. passed away in 2012.
Identification
DOI: https://doi.org/10.1016/j.jstrokecerebrovasdis.2013.11.015
Copyright
© 2014 National Stroke Association. Published by Elsevier Inc. All rights reserved.
