Background: Stroke remains a major health burden worldwide. The incidence and prevalence rates
of stroke are decreasing in developed countries, an opposite trend is taking place
in the Asia Pacific, where an increasing number of patients are being diagnosed with
acute stroke. The results of the present study on acute stroke in multi-ethnic Malaysia
will significantly contribute to the global stroke epidemiological data. We aimed
to present epidemiological data of stroke including incidence and prevalence rates
as well as associated risk factors from a prospective nationwide hospital-based registry
from 2010 to 2014. Methods: Patients diagnosed with stroke upon admission at the hospital were prospectively
enrolled into the registry from January 1, 2010, to December 31, 2014. Descriptive
analyses were performed. Results: A total of 7668 patients were available for analysis. On average, patients were aged
62.7 years (standard deviation of 12.5). Ischemic stroke accounts for 79.4% of the
cohort with a slightly higher proportion of male patients (55%). Ischemic stroke incidence
is estimated to increase annually by 29.5% and hemorrhagic stroke by 18.7%. Hypertension
is a major risk factor for both ischemic and hemorrhagic strokes regardless of stroke
event with an excess of 8.4% hypertensive female compare to male patients (P ≤ .001). Majority of patients with ischemic and hemorrhagic strokes experienced mild
and moderate stroke with 11.7% and 21.1%, respectively, documented as severe (P ≤ .001). Conclusions: The incidence and prevalence of stroke in Malaysia increased dramatically in the
5-year study period. Therefore, implementation of risk factor control strategies is
important to prevent further increase of stroke burden in the country.
Key Words
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Article info
Publication history
Published online: August 31, 2015
Accepted:
July 29,
2015
Received in revised form:
July 22,
2015
Received:
June 16,
2015
Footnotes
Yvonne Y.L. Lee is an employee of Pfizer Malaysia Sdn Bhd. All other authors declared no conflicts of interest.
Identification
DOI: https://doi.org/10.1016/j.jstrokecerebrovasdis.2015.07.025
Copyright
© 2015 National Stroke Association. Published by Elsevier Inc. All rights reserved.
