Background
Nutritional status is associated with the functional recovery of stroke patients.
This study aimed to examine the influence of the combination of body mass index (BMI)
and serum albumin level on functional recovery in subacute stroke patients.
Methods
This retrospective cohort study included 259 subacute stroke patients (mean age 68.9 ± 12.3
years). Patients were categorized into 4 groups according to their BMI and serum albumin
level: group 1, low BMI (<18.5 kg/m2) and low serum albumin level (<3.5 g/dL); group 2, low BMI and high serum albumin
level (≥3.5 g/dL); group 3, normal weight (≥18.5 kg/m2) and low serum albumin level; and group 4, normal weight and high serum albumin level.
The outcome variable was the motor subscale of the Functional Independence Measure
(M-FIM) effectiveness. We defined the first quartile of M-FIM effectiveness as poor
functional recovery. Multivariate logistic regression analysis was performed to examine
the influence of the combination of BMI and serum albumin level on poor functional
recovery.
Results
Multivariate logistic regression analysis adjusted for baseline characteristics (reference,
group 4) showed that group 1 was mostly associated with a significant risk of poor
functional recovery (odds ratio, 4.13; 95% confidence interval, 1.53-11.15).
Conclusions
Our results suggested that the combination of low BMI and low serum albumin level
was more significantly associated with poor functional recovery in subacute stroke
patients than either factor alone. The combination of BMI and serum albumin level
should be taken into account when predicting functional recovery in subacute stroke
patients.
Key Words
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Article info
Publication history
Published online: November 14, 2016
Accepted:
October 10,
2016
Received in revised form:
September 16,
2016
Received:
July 13,
2016
Identification
DOI: https://doi.org/10.1016/j.jstrokecerebrovasdis.2016.10.008
Copyright
© 2017 National Stroke Association. Published by Elsevier Inc. All rights reserved.
