Rotation thromboelastometry is a viscoelastometric method that provides a rapid assessment
of a patient's hemostatic processes in emergency settings, allowing prompt identification
of specific coagulation abnormalities. Its results thus might guide targeted replacement
therapy in hemorrhagic conditions, in case of platelet or coagulation factor deficiency,
or hyperfibrinolysis, which is difficult to identify otherwise. Although currently
used in emergency and traumatic surgery, there are limited data about thromboelastometry
in ischemic stroke, particularly in monitoring the coagulative response to recombinant
tissue plasminogen activator after intravenous thrombolysis (IVT). Here we report
a case of ischemic stroke complicated by a remote asymptomatic intracranial hemorrhage
after IVT and additional endovascular therapy that has been successfully treated with
intravenous infusion of tranexamic acid after the detection of the status of hyperfibrinolysis
provided by thromboelastometry. Further studies are needed to provide the potential
usefulness of thromboelastometry and tranexamic acid in ischemic stroke complicated
by intracranial bleeding.
Key Words
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Article info
Publication history
Published online: November 23, 2016
Accepted:
October 29,
2016
Received in revised form:
September 14,
2016
Received:
June 10,
2016
Identification
DOI: https://doi.org/10.1016/j.jstrokecerebrovasdis.2016.10.039
Copyright
© 2017 National Stroke Association. Published by Elsevier Inc. All rights reserved.
