Abstract
Background and Aims: To date, the correlation between sarcopenia, which exists before a stroke, and acute
stroke outcome remains partially understood. This study aims to evaluate the skeletal
muscle mass deficit using the bioelectrical impedance analysis in patients with acute
ischemic stroke. Methods: We enrolled 164 geriatric patients with acute ischemic stroke (108 males and 56 females)
who underwent the bioelectrical impedance analysis. We evaluated clinical outcomes
and their impact on patients with the skeletal muscle mass deficit determined using
the skeletal muscle mass index. Results: The skeletal muscle mass deficit was obtained using the bioelectrical impedance analysis
in 101 patients. Patients with the skeletal muscle mass deficit determined by the
skeletal muscle mass index exhibited severe neurological impairment and functional
status on admission; moreover, they tended to display poor functional outcome and
prolonged hospital stay. Logistic regression analysis revealed that the skeletal muscle
mass deficit remained an independent poor outcome predictor. Conclusions: This study establishes the presence of the skeletal muscle mass deficit in over half
patients with acute ischemic stroke. Furthermore, the skeletal muscle mass deficit
correlates with neurological impairment owing to stroke with poorer functional prognosis.
Key Words
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Article info
Publication history
Published online: January 14, 2020
Accepted:
December 22,
2019
Received in revised form:
November 28,
2019
Received:
August 28,
2019
Footnotes
Grant support: None.
Identification
DOI: https://doi.org/10.1016/j.jstrokecerebrovasdis.2019.104623
Copyright
© 2019 Elsevier Inc. All rights reserved.
