Abstract
Objective
Although several studies have reported that some meteorological factors such as ambient
temperature and atmospheric pressure, affect the incidence of spontaneous intracerebral
hemorrhage (ICH), the correlation remains unclear. This retrospective time-series
analysis was aimed to clarify the effects of meteorological parameters on the incidence
of ICH.
Materials and Methods
Data of patients with ICH were obtained from a population-based survey of acute stroke
patients between April 2016 and March 2019. All days during the study period were
categorized into “no ICH day” when no ICHs occurred, “single ICH day” when only one
ICH occurred, and “cluster day” when two or more ICHs occurred. Meteorological data
were compared for among the three categories.
Results
1,691 ICH patients from 19 hospitals were registered. In a total of 1,095 days, 250
were categorized as no ICH days, 361 as single ICH days, and 484 as cluster days.
Daily ambient temperature declined in parallel with the daily number of ICHs, and
it was a significant predictor for single ICH days and cluster days. Furthermore,
the incidence of ICH in patients aged 65 years or above, men, those who emerged at
home, those with modified Rankin Scale 3-5; and those with hypertension; and ICHs
in the basal ganglia, brain stem, and cerebellum were more likely to be affected by
low ambient temperature.
Conclusion
Daily ambient temperature was significantly associated with ICH incidence. Patients’
activity, history of hypertension, and location of hemorrhage were also related to
the impact of low ambient temperature on the incidence of ICH.
Key Words
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Journal of Stroke and Cerebrovascular DiseasesAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Meteorological factors and the onset of hypertensive intracerebral hemorrhage.Int J Biometeorol. 2004; 49: 86-90
- Differing temporal patterns of onset in subgroups of patients with intracerebral hemorrhage.Stroke. 2000; 31: 1538-1544
- A population-based study of the associations of stroke occurrence with weather parameters in Siberia, Russia (1982-92).Eur J Neurol. 2000; 7: 171-178
- Weather as a trigger of stroke. Daily meteorological factors and incidence of stroke subtypes.Cerebrovasc Dis. 2008; 26 (Basel, Switzerland): 348-354
- Is stroke incidence related to season or temperature? The Oxfordshire community stroke project.Lancet. 1996; 347 (London, England): 934-936
- Higher stroke incidence in the spring season regardless of conventional risk factors: Takashima Stroke Registry, Japan, 1988-2001.Stroke. 2008; 39: 745-752
- A study of weekly and seasonal variation of stroke onset.Int J Biometeorol. 2002; 47: 13-20
- Seasonal variation in stroke incidence in Hisayama, Japan.Stroke. 1990; 21: 1262-1267
- Seasonal variation in types of stroke and its common risk factors.Mymensingh Med J MMJ. 2012; 21: 13-20
- Seasonality of stroke in Finland.Ann Med. 2017; 49: 310-318
- Stroke in the Lehigh valley: seasonal variation in incidence rates.Stroke. 1987; 18: 38-42
- Revealing the association between cerebrovascular accidents and ambient temperature: a meta-analysis.Int J Biometeorol. 2017; 61: 821-832
- An analysis of admissions from 155 United States hospitals to determine the influence of weather on stroke incidence.Jo Clin Neurosci Off J Neurosurg Socf Australas. 2011; 18: 618-623
- Involvement of meteorological factors and sex in the occurrence of subarachnoid hemorrhage in Japan.Neurol Med Chir. 2008; 48: 101-107
- Updated world map of the Köppen-Geiger climate classification.Hydrol Earth Syst Sci. 2007; 11: 1633-1644
- Impact of temperature decline from the previous day as a trigger of spontaneous subarachnoid hemorrhage: case-crossover study of prefectural stroke database.J Neurosurg. 2019; : 1-9
- Sensitivity analysis in observational research: introducing the E-value.Ann Intern Med. 2017; 167: 268-274
- Blood pressure response to patterns of weather fluctuations and effect on mortality.Hypertension. 2013; 62 (Dallas, Tex : 1979): 190-196
- Relationship between blood pressure and outdoor temperature in a large sample of elderly individuals: the three-city study.Arch Intern Med. 2009; 169: 75-80
- Ambient temperature and stroke risk: evidence supporting a short-term effect at a population level from acute environmental exposures.Stroke. 2018; 49: 255-261
- Excess cardiovascular mortality associated with cold spells in the Czech Republic.BMC Public Health. 2009; 9: 19
- Seasonal blood pressure variation and its relationship to environmental temperature in healthy elderly Japanese studied by home measurements.Clin Exp Hypertens. 2010; 32 (New York, NY: 1993): 8-12
- Seasonal variation in home blood pressure measurements and relation to outside temperature in Japan.Clin Exp Hypertens. 2011; 33 (New York, NY: 1993): 153-158
- Average temperature, diurnal temperature variation, and stroke hospitalizations.J Stroke Cerebrovasc Dis Off J Natl Stroke Assoc. 2016; 25: 1489-1494
- Climatic and seasonal circumstances of hypertensive intracerebral hemorrhage in a worldwide cohort.Stroke. 2017; 48: 3384-3386
- Incidence, management and short-term outcome of stroke in a general population of 1.4 million Japanese-Shiga stroke registry.Circ J Off J Jpn Circ Soc. 2017; 81: 1636-1646
Article info
Publication history
Published online: October 29, 2021
Accepted:
October 1,
2021
Received in revised form:
September 25,
2021
Received:
February 7,
2021
Identification
DOI: https://doi.org/10.1016/j.jstrokecerebrovasdis.2021.106156
Copyright
© 2021 Elsevier Inc. All rights reserved.
