Abstract
Objective
To determine the odds of stroke in women of reproductive age who have had metabolic
or bariatric surgery (MBS).
Methods
We used the National Inpatient Sample (NIS), a publicly available dataset that samples
20% of hospital discharges. The study population includes women between the ages of
20 and 44 without a maternal admission code. Weighted logistic regression analyses
were conducted to assess the odds of stroke in women with history of MBS compared
to other women of reproductive age. Adjustment of odds was done for the following
covariates: age, race, primary payer, severity of illness, depression, and obesity.
Results
Women with a history of MBS had 52% lower adjusted odds of having a stroke than women
who did not have MBS (OR = 0.48, 95%CI = 0.42-0.55). Additionally, women who had MBS
had lower odds of risk factors for stroke, including diabetes (OR = 0.61, 95%CI =
0.59-0.63), hypertension (OR = 0.82, 95%CI = 0.81-0.84), hypercholesterolemia (OR=0.72,
95%CI =0.68-0.77), and migraine with aura (OR = 0.86, 95%CI = 0.74-0.99).
Conclusions
Among women of reproductive age with a history of MBS, there were lower odds of having
a stroke and stroke risk factors when compared to women who did not have MBS. Additionally,
this study showed a modest decrease in the odds of stroke among women with obesity
when adjusted for other risk factors. Future research should focus on examining this
finding further, with a focus on the moderation of the impact of having obesity on
stroke risk independent of other stroke risk factors.
Keywords
Abbreviations:
MBS (metabolic or bariatric surgery), NIS (National Inpatient Sample), AHRQ (Agency for Healthcare Research and Quality)To read this article in full you will need to make a payment
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Article info
Publication history
Published online: October 05, 2022
Accepted:
September 26,
2022
Received in revised form:
September 23,
2022
Received:
April 4,
2022
Identification
DOI: https://doi.org/10.1016/j.jstrokecerebrovasdis.2022.106814
Copyright
© 2022 Elsevier Inc. All rights reserved.
