Abstract
Objectives
The hyperdense artery sign on non-contrast computed tomography-reconstructed images
is useful for identifying large vessel occlusion in acute ischemic stroke. This study
aimed to assess its efficacy in patients with large vessel occlusion treated with
mechanical thrombectomy.
Materials and methods
: This retrospective and prospective single-centered study from June 2019 to May 2021
evaluated the use of non-contrast computed tomography-reconstructed images for detecting
hyperdense artery sign to identify large vessel occlusion from June 2020 to May 2021.
We registered consecutive potential candidates for mechanical thrombectomy due to
suspected stroke and assessed the accuracy of hyperdense artery sign on non-contrast
computed tomography-reconstructed images for large vessel occlusion in the hyperacute
setting. Non-contrast computed tomography images were reconstructed into maximum intensity
projection images with iterative reconstruction algorithms to detect hyperdense artery
signs. We compared the door-to-puncture time and functional outcome at 90 days before
and after employing non-contrast computed tomography-reconstructed images in patients
with large vessel occlusion treated with mechanical thrombectomy.
Results
The cohort included 82 patients, wherein 47 were treated with mechanical thrombectomy.
The sensitivity (96%) and specificity (94%) of hyperdense artery sign on non-contrast
computed tomography-reconstructed images for large vessel occlusion were performed.
The door-to-puncture time was significantly shortened after using non-contrast computed
tomography-reconstructed images (49 versus 28 min, p = 0.001), but the functional
outcome at 90 days remained unchanged.
Conclusions
Non-contrast computed tomography-reconstructed images, as a vascular imaging tool
for mechanical thrombectomy, can reduce workflow time in hospitals by identifying
large vessel occlusion with high sensitivity and specificity.
Keywords
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Article info
Publication history
Published online: November 12, 2022
Accepted:
October 11,
2022
Received in revised form:
October 8,
2022
Received:
August 17,
2022
Identification
DOI: https://doi.org/10.1016/j.jstrokecerebrovasdis.2022.106846
Copyright
© 2022 Elsevier Inc. All rights reserved.
