Highlights
- •Mexican Americans showed lower cognitive performance compared to non-Hispanic white adults at post-stroke baseline and 3 months following stroke.
- •Cognitive trajectories from 0-3 months following stroke did not differ between Mexican Americans and non-Hispanic white adults.
- •Further research is needed to identify factors contributing to ethnic disparities in cognitive outcomes after stroke.
Abstract
Objectives
We examined whether cognitive trajectories from 0-3 months after stroke differ between
Mexican Americans (MAs) and non-Hispanic white (NHW) adults.
Materials and Methods
The sample included 701 participants with ischemic stroke (62% MA; 38% NHW) from the
population-based stroke surveillance study, the Brain Attack Surveillance in Corpus
Christi (BASIC) Project, between 2008-2013. The outcome was the modified Mini Mental
State Examination (3MSE, range 0-100 lower scores worse). Linear mixed effects models
were utilized to examine the association between ethnicity and cognitive trajectories
from 0-3 months following stroke, adjusting for confounders.
Results
MAs were younger, had lower educational attainment, and fewer had health insurance
than NHWs (all p< 0.01). A smaller proportion of MAs were rated by informants as exhibiting pre-stroke
cognitive decline than NHW (p < .0.05). After accounting for confounders, MAs demonstrated lower cognitive performance
at post-stroke baseline and at 3-months following stroke (-2.00; 95% CI =-3.92, -0.07).
Cognitive trajectories from 0-3 months following stroke were indicative of modest
cognitive recovery (increase of 0.034/day, 95% CI =0.030-0.036) and did not differ
between MAs and NHWs (p = 0.68).
Conclusion
We found no evidence that cognitive trajectories in the first three months following
stroke differed between MAs and NHWs. MAs demonstrated lower cognitive performance
shortly after stroke and at three months following stroke compared to NHWs. Further
research is needed to identify factors contributing to ethnic disparities in cognitive
outcomes after stroke.
Keywords
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Article info
Publication history
Published online: November 29, 2022
Accepted:
November 19,
2022
Received in revised form:
November 1,
2022
Received:
August 12,
2022
Identification
DOI: https://doi.org/10.1016/j.jstrokecerebrovasdis.2022.106902
Copyright
© 2022 Elsevier Inc. All rights reserved.
