Correspondence| Volume 32, ISSUE 2, 106925, February 2023

Ischemic stroke-related takotsubo syndrome and atrial fibrillation: Some answers to vexing questions

      To the Editor:
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'


      Subscribe to Journal of Stroke and Cerebrovascular Diseases
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect


        • Min J.
        • Young G.
        • Umar A.
        • et al.
        Neurogenic cardiac outcome in patients after acute ischemic stroke: the brain and heart connection.
        J Stroke Cerebrovasc Dis. 2022; 31 (Online ahead of print)106859
      1. Oldgren J., Åsberg S., Hijazi Z., Wester P., Bertilsson M., Norrving B.; National TIMING Collaborators.Circulation. Early Versus Delayed Non-Vitamin K Antagonist Oral Anticoagulant Therapy After Acute Ischemic Stroke in Atrial Fibrillation (TIMING): a Registry-Based Randomized Controlled Noninferiority Study. 2022;146(14):1056-1066.

        • Madias JE.
        Neurogenic stunned myocardium vs. Takotsubo syndrome: we should stop making a distinction.
        Int J Cardiol. 2014; 177: 166
        • Madias JE.
        What is the real prevalence of takotsubo syndrome in patients admitted with aneurysmal subarachnoid hemorrhage?.
        Clin Neurol Neurosurg. 2016; 145: 104-105
        • Samuels MA.
        The brain-heart connection.
        Circulation. 2007; 116: 77-84
        • Madias JE.
        A proposal for a noninvasive monitoring of sympathetic nerve activity in patients with takotsubo syndrome.
        Med Hypotheses. 2017; 109: 97-101
        • Uradu A.
        • Wan J.
        • Doytchinova A.
        • Wright K.C.
        • Lin A.Y.T.
        • Chen L.S.
        • et al.
        Skin sympathetic nerve activity precedes the onset and termination of paroxysmal atrial tachycardia and fibrillation.
        Heart Rhythm. 2017; 14: 964-971