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Comment on vaccine associated benign headache and cutaneous hemorrhage after ChAdOx1 nCoV-19 vaccine

      Dear Editor, we would like to share ideas on the publication “Vaccine associated benign headache and cutaneous hemorrhage after ChAdOx1 nCoV-19 vaccine: A cohort study
      • Schultz NH
      • Søraas AVL
      • Sørvoll IH
      • Akkök ÇA
      • Vetlesen A
      • Bhamra JS
      • Ahlen MT
      • Holme PA
      • Aamodt AH
      • Skagen K
      • Skattør TH
      • Skjelland M
      • Wiedmann MK.
      Vaccine associated benign headache and cutaneous hemorrhage after ChAdOx1 nCoV-19 vaccine: a cohort study.
      .” If these symptoms are a minor form of VITT, with a possibility for worsening, such as in the case of a second vaccination dose, or a new entity of vaccine consequences, Schultz et al. explored this
      • Schultz NH
      • Søraas AVL
      • Sørvoll IH
      • Akkök ÇA
      • Vetlesen A
      • Bhamra JS
      • Ahlen MT
      • Holme PA
      • Aamodt AH
      • Skagen K
      • Skattør TH
      • Skjelland M
      • Wiedmann MK.
      Vaccine associated benign headache and cutaneous hemorrhage after ChAdOx1 nCoV-19 vaccine: a cohort study.
      . The combination of headaches and subcutaneous hemorrhage, according to Schultz et al., did not indicate VITT, and no other distinct coagulation problem or cerebral pathology was discovered. In addition to platelet counts and D-dimer, Schultz et al. noted that symptoms that initially resemble VITT call for caution and a low threshold for a clinical evaluation
      • Schultz NH
      • Søraas AVL
      • Sørvoll IH
      • Akkök ÇA
      • Vetlesen A
      • Bhamra JS
      • Ahlen MT
      • Holme PA
      • Aamodt AH
      • Skagen K
      • Skattør TH
      • Skjelland M
      • Wiedmann MK.
      Vaccine associated benign headache and cutaneous hemorrhage after ChAdOx1 nCoV-19 vaccine: a cohort study.
      .
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      References

        • Schultz NH
        • Søraas AVL
        • Sørvoll IH
        • Akkök ÇA
        • Vetlesen A
        • Bhamra JS
        • Ahlen MT
        • Holme PA
        • Aamodt AH
        • Skagen K
        • Skattør TH
        • Skjelland M
        • Wiedmann MK.
        Vaccine associated benign headache and cutaneous hemorrhage after ChAdOx1 nCoV-19 vaccine: a cohort study.
        J Stroke Cerebrovasc Dis. 2022 Nov 17; 32106860
        • Kebayoon A
        • Wiwanitkit V.
        Dengue after COVID-19 vaccination: possible and might be missed.
        Clin Appl Thromb Hemost. 2021; 2710760296211047229

      Linked Article

      • Response to Letter to the Editor
        Journal of Stroke and Cerebrovascular Diseases
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          We thank the authors for their interest in our article and the thoughtful comments. As they correctly point out, the association between the first vaccination with ChAdOx1 nCov -19 vaccine and the described symptoms in our article does not prove any causality. However, cutaneous hemorrhages and headaches were frequently reported side effects after vaccination with ChAdOx1 nCov-19 in the Norwegian corona study cohort in young and previously healthy subjects. In lack of previous experience, there was a fear that these symptoms may have represented a mild form of VITT.
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