We thank the authors for their interest in our article and the thoughtful comments.
As they correctly point out, the association between the first vaccination with ChAdOx1
nCov -19 vaccine and the described symptoms in our article does not prove any causality.
However, cutaneous hemorrhages and headaches were frequently reported side effects
after vaccination with ChAdOx1 nCov-19 in the Norwegian corona study cohort in young
and previously healthy subjects. In lack of previous experience, there was a fear
that these symptoms may have represented a mild form of VITT. Fortunately, this was
not the case and none of the subjects with these mild, vaccine associated symptoms
developed increasing side effects later on. We think that this would be reassuring
for people to take vaccines, even if mild side effects may occur. In our opinion,
the trust of people in health-care is increased by transparency and honest discussions
of findings, although causality is not always clear.
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Article info
Publication history
Published online: January 20, 2023
Publication stage
In Press Corrected ProofIdentification
DOI: https://doi.org/10.1016/j.jstrokecerebrovasdis.2022.106961
Copyright
© 2022 Published by Elsevier Inc.
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- Comment on vaccine associated benign headache and cutaneous hemorrhage after ChAdOx1 nCoV-19 vaccineJournal of Stroke and Cerebrovascular Diseases
- PreviewDear Editor, we would like to share ideas on the publication “Vaccine associated benign headache and cutaneous hemorrhage after ChAdOx1 nCoV-19 vaccine: A cohort study1.” If these symptoms are a minor form of VITT, with a possibility for worsening, such as in the case of a second vaccination dose, or a new entity of vaccine consequences, Schultz et al. explored this1. The combination of headaches and subcutaneous hemorrhage, according to Schultz et al., did not indicate VITT, and no other distinct coagulation problem or cerebral pathology was discovered.
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