Abstract
Objectives
Time from onset to reperfusion affects mortality and favorable outcomes in patients
with acute ischemic stroke (AIS). To evaluate effects of a real-time feedback mobile
application on critical time intervals and functional outcomes in stroke emergency
management.
Methods
We recruited patients with clinically suspected acute stroke from December 1st, 2020
until July 30st, 2022. All Patients had a non-contrast computed tomography (CT) and
were included only if they had AIS. We divided the patients into two groups based
on the date of availability on mobile application: pre-APP group and post-APP group.
Onset to Door time (ODT), Door to Imaging Time (DIT), Door to Needle Time (DNT), Door
to Puncture Time (DPT), Door to Recanalization Time (DRT), National Institutes of
Health Stroke Scale (NIHSS) and modified Rankin Scale (mRS) were compared between
two groups.
Results
We retrospectively enrolled 312 AIS patients who were assigned into the pre-APP group
(n = 159) and post-APP group (n = 153). The median ODT time and median admission NIHSS score were not significantly
different between the two groups at baseline assessment. The median (IQR) DIT [44
(30-60) min vs 28 (20-36) min, P < 0.01] and DNT [44 (36.25-52) min vs 39 (29-45) min, P = 0.02] both decreased significantly in two groups. However, median DPT and DRT time
showed no significant differences. The proportion of mRS score of 0 to 2 at day 90
was significantly higher in the post-App group than in the pre-App group, at 82.4%
and 71.7%, respectively (dominance ratio OR=1.84, 95% CI: 1.07 to 3.16, P = 0.03).
Conclusion
The present findings indicate that the real-time feedback of stroke emergency management
used by a mobile application have potential for shortening the DIT and DNT time and
improve the prognosis of stroke patients.
Keywords
Abbreviations:
AIS (acute ischemic stroke), APP (application), DNT (door-to-needle time)To read this article in full you will need to make a payment
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Article info
Publication history
Published online: February 14, 2023
Accepted:
February 7,
2023
Received in revised form:
February 5,
2023
Received:
October 22,
2022
Identification
DOI: https://doi.org/10.1016/j.jstrokecerebrovasdis.2023.107055
Copyright
© 2023 Elsevier Inc. All rights reserved.
