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Background. Disease of the major vessels in the neck can disrupt autoregulation and lead to
changes in the cerebral blood flow and cerebral autoregulation. These changes can
be reflected by means of cerebral oxygen saturation. Methods. We measured cerebral oxygen saturation in 20 patients with atherosclerotic disease
of the carotid and vertebral arteries and compared results with 10 normal subjects.
Saturation was measured using a noninvasive near-infrared device, the transcranial
cerebral oximeter. Results. There were marked decreases in cerebral oxygen saturation in patients with carotid-vertebral
artery disease when the position of the patient was changed, from supine to erect.
Conclusion. Changes in regional cerebral oxygen saturation inpatients with carotid-vertebral
artery disease may reflect disruption of cerebral autoregulation.
Key words
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Article info
Publication history
Accepted:
December 13,
1996
Received:
November 27,
1995
Identification
Copyright
© 1997 National Stroke Division. Published by Elsevier Inc.
