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Rapid Communication| Volume 6, ISSUE 5, P368-369, July 1997

Hypoglycemic hemiplegia: Insulinoma masquerading as stroke

  • Vijay Shanmugam
    Correspondence
    Address reprint requests to Vijay Shanmugam, MD, Department of Neurological Science, 1725 West Harrison, Suite 1106, Chicago, IL 60612.
    Affiliations
    Section of Cerebrovascular Disease, Center for Stroke Research, Department of Neurological Sciences, Rush Medical College, Chicago, IL., USA

    Northwest Neurology Ltd, Hoffman Estates, IL., USA
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  • Simon Zimnowodzki
    Affiliations
    Section of Cerebrovascular Disease, Center for Stroke Research, Department of Neurological Sciences, Rush Medical College, Chicago, IL., USA

    Northwest Neurology Ltd, Hoffman Estates, IL., USA
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  • Jeffrey Curtin
    Affiliations
    Section of Cerebrovascular Disease, Center for Stroke Research, Department of Neurological Sciences, Rush Medical College, Chicago, IL., USA

    Northwest Neurology Ltd, Hoffman Estates, IL., USA
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  • Philip B. Gorelick
    Affiliations
    Section of Cerebrovascular Disease, Center for Stroke Research, Department of Neurological Sciences, Rush Medical College, Chicago, IL., USA

    Northwest Neurology Ltd, Hoffman Estates, IL., USA
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      This paper is only available as a PDF. To read, Please Download here.
      We report a patient with recurrent episodes of hemiplegia caused by hypoglycemia. Investigations revealed an insulinoma, which was surgically removed. After this, the blood glucose level normalized and the patient remained asymptomatic for 9 months. We discuss pathophysiological mechanisms whereby hypoglycemia might cause focal neurological deficit.

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      References

        • Malouf R
        • Brust JCM
        Hypoglycemia: causes, neurological manifestations, and outcome.
        Ann Neurol. 1985; 17: 421-430
        • Foster JW
        • Hart RG
        Hypoglycemic hemiplegia: two cases and a clinical review.
        Stroke. 1987; 18: 944-946
        • Daggett P
        • Nabarro J
        Neurological aspects of insulinomas.
        Postgrad Med J. 1984; 60: 577-581
        • Suresh TG
        • Gupta SK
        • Satishchandra P
        Hypoglycemic hemiplegia due to insulinoma.
        J Assoc Physicians India. 1993; 41: 677-678
        • Auer RN
        • Siesjo BK
        Biological differences between ischemia, hypoglycemia, and epilepsy.
        Ann Neurol. 1988; 24: 699-707
        • MacDonald JT
        • Brown DR
        Acute hemiparesis in juvenile insulin-dependent diabetes mellitus.
        Neurology. 1979; 29 (JIDDM): 893-896
        • Pornoy HD
        Transient “ischemic” attacks produced by carotid stenosis and hypoglycemia.
        Neurology. 1965; 15: 830-832
        • Meyer JS
        • Portnoy HD
        Localized cerebral hypoglycemia simulating stroke.
        Neurology. 1958; 8: 601-614
        • Wallis WE
        • Donaldson I
        • Scott RS
        • Wilson J
        Hypoglycemia maquerading as cerebrovascular disease.
        Ann Neurol. 1985; 18 (hypoglycemic hemiplegia): 510-512
        • Shintani S
        • Tsuruoka S
        • Shiigai T
        Hypoglycemic hemiplegia: a repeat SPECT study.
        J Neurol Neurosurg Psychiatry. 1993; 56: 700-701